Modification catalogue

Modifications are priced on top of the oligo. Combinations are checked before synthesis, not after.

5′ fluorescent dyes

6-FAM · TET · JOE · HEX · Cy3 · Cy5 · Cy5.5 · TAMRA · ROX · Texas Red

3′ quenchers

BHQ-1 · BHQ-2 · BHQ-3 · Dabcyl · Iowa Black FQ · Iowa Black RQ · MGB

Attachment chemistry

5′/3′ amino C6 · 5′/3′ thiol C6 · biotin · biotin-TEG · azide · DBCO · alkyne

Backbone & sugar

phosphorothioate · 2′-O-methyl · 2′-fluoro · LNA · inverted dT · dideoxy-C

Spacers & linkers

C3 spacer · C6 spacer · C12 spacer · Spacer 9 · Spacer 18 · dSpacer · PC linker

Base analogues

inosine · 5-bromo-dU · 2-aminopurine · 8-oxo-dG · pyrrolo-dC · 5-methyl-dC · uracil

Dye and quencher combinations can be checked against published spectral ranges with the dye–quencher checker before you order.
More than four modifications on one oligo, or something not listed here? That is a design-help case, not a dead end — send us the requirement and you get a design and a price within one business day.